Témbongkeun sumber pikeun Kortison

{{distinguish|kortisol}}
{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 456660597
| pronounce     = {{IPAc-en|ˈ|k|ɔːr|t|ᵻ|s|oʊ|n}}, {{IPAc-en|ˈ|k|ɔːr|t|ᵻ|z|oʊ|n}}
| ImageFile = Cortison.svg
| ImageFile1 = Cortisone-3D-balls.png
| IUPACName = (8''S'',9''S'',10''R'',13''S'',14''S'',17''R'')-17-Hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione
| OtherNames = 17α,21-Dihydroxypregn-4-ene-3,11,20-trione; 17α,21-Dihydroxy-11-ketoprogesterone; 17α-Hydroxy-11-dehydrocorticosterone
|Section1={{Chembox Identifiers
| UNII_Ref = {{fdacite|changed|FDA}}
| IUPHAR_ligand = 5171
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 111861
| InChI = 1/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
| InChIKey = MFYSYFVPBJMHGN-ZPOLXVRWBW
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = MFYSYFVPBJMHGN-ZPOLXVRWSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 193441
| CASNo = 53-06-5
| PubChem = 222786
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07749
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 16962
| SMILES = O=C(CO)[C@@]3(O)CC[C@H]2[C@@H]4CC\C1=C\C(=O)CC[C@]1(C)[C@H]4C(=O)C[C@@]23C
| MeSHName = Cortisone
  }}
|Section2={{Chembox Properties
| C=21 | H=28 | O=5
| Appearance = 
| Density = 
| MeltingPtC = 220 to 224
| BoilingPt = 
  }}
|Section6={{Chembox Pharmacology
| ATCCode_prefix = H02
| ATCCode_suffix = AB10
| ATC_Supplemental = {{ATC|S01|BA03}}
}}
|Section7={{Chembox Hazards
| MainHazards = 
| FlashPt = 
| AutoignitionPt = 
  }}
}}
'''Kortison''' nyaéta [[hormon stériod]] [[prégnana]] (21-karbon) anu dikaluarkeun ku [[kelenjar adrénal]] dina nyanghareupan setrés. Sacara wangun kimia, ieu sanyawa kortikostéroid anu deukeut jeung [[kortisol]]. Kortison biasa dipaké natambaan rupa-rupa nyeri, ku cara neken sistem imun, ku kituna ngurangan peradangan/inflamasi anu dibarung ku nyeri jeung bareuh lebah nu [[tatu]]. Lamun dipaké matuh, kortison bisa bahya ogé. <ref name="mayo">{{Cite web|url=http://www.mayoclinic.com/health/cortisone-shots/MY00268|title=Cortisone shots|publisher=MayoClinic.com|accessdate=July 31, 2013}}</ref> <ref name="mayorisk2">{{Cite web|url=https://www.mayoclinic.org/steroids/art-20045692|title=Prednisone and other corticosteroids: Balance the risks and benefits|publisher=MayoClinic.com|accessdate=2017-12-21}}</ref> 

== Pangaruh jeung mangpaat ==
Kortison, glukokortikoid, jeung [[Adrénalin|épinéfrin]] (adrénalin) ngaronjatkeun tekanan getih sarta nyiapkeun awa pikeun [[réspon lawan atawa ngejat]]. 

Injéksi kortison bisa dipaké pikeun natambaan nyeri & bareuh saharitaeun dina [[Inflamasi|peradangan]] sendi, urat, atawa bursa, upamana dina [[tuur]], [[siku]], jeung taktak.<ref name="mayo">{{Cite web|url=http://www.mayoclinic.com/health/cortisone-shots/MY00268|title=Cortisone shots|publisher=MayoClinic.com|accessdate=July 31, 2013}}</ref> 

Kortison ogé bisa dipaké pikeun ngurangan réspon imun jalma anu boga kasakit otoimun atawa nalika natambaan cangkok organ pikeun nyegah panolakan cangkokan. Suprési sistem imun ogé penting dina ngubaran kondisi peradangan. <ref>{{Cite web|url=http://www.medicinenet.com/cortisone_injection/article.htm|title=Cortisone Injection (Corticosteroid Injection) of Soft Tissues & Joints|last=Driver|first=Catherine|last2=Shiel|first2=William|publisher=MedicineNet.com|accessdate=August 7, 2013}}</ref> 

== Rujukan ==
{{Reflist|30em}}

== Bacaeun salajengna ==

* {{Cite book|last=Bonagura J., DVM|title=Current Veterinary Therapy|year=2000|pages=321–381|volume=13|display-authors=etal}} 
* {{Cite journal|last=Ingle DJ|date=October 1950|title=The biologic properties of cortisone: a review|url=http://jcem.endojournals.org/cgi/pmidlookup?view=long&pmid=14794756|journal=J. Clin. Endocrinol. Metab.|volume=10|issue=10|pages=1312–54|doi=10.1210/jcem-10-10-1312|pmid=14794756}} 
* {{Cite journal|last=Woodward R. B.|last2=Sondheimer F.|last3=Taub D.|year=1951|title=The Total Synthesis of Cortisone|journal=Journal of the American Chemical Society|volume=73|issue=8|pages=4057|doi=10.1021/ja01152a551}} 
{{Hormon}}